PTRL West

Experimental Study Descriptions

• Environmental Assessment (Fate Testing):  

Studies conducted to determine the environmental degradation and disposition of drugs are designed to include the typical parameters related to hydrolytic, photochemical and biological degradation. Biomimetic systems, such as chemical oxidants and cell cultures can also be utilized.

• Analytical Chemistry:  

Method development and validation for drugs and their metabolites in blood, plasma and urine involving GC, HPLC, GC-MS, and LC-MS(MS).

Clinical sample analysis.

Metabolism and disposition in rodents (ADME) utilizing radiotracers (refer to rat section of Metabolism page).

Total Organic Carbon (TOC) for water samples.

Agrochemicals
Industrial Chemicals and REACH Program
Pharmaceuticals

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Last modified: August 07, 2007