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Publication Record for Katsumi Sugiyama:1. Sugiyama, K., Trager, W. F.: Prochiral selectivity and intramolecular isotope effects in the cytochrome P450 catalyzed- -hydroxylation of cumene. Biochemistry, 25, 7336-7343 (1986) 2. Decker, C, Sugiyama, K., Underwood, M and Correia, M. A.: Inactivation of hepatic Cyt.P450 by spironolactone. Biochem. Biophys. Res. Commun. 136, 1162-1169 (1986) 3. Correia, M. A., Decker, C., Sugiyama, K., Caldera, P., Bornheim, L., Wrighton, S. A., Rettie, A. E. and Trager, W. F.: Degradation of rat hepatic Cyt.P450 heme by 3,5-Dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts. Arch. Biochem. Biophys. 236, 436-451 (1987) 4. Lunneta,J. M., Sugiyama, K., and Correia, M. A.: Secobarbital mediated inactivation of rat liver Cyt.P450 isozymes, Mol. Pharmacol., 35, 10-17 (1989) 5. Sugiyama,K., Yao.K. and Correia, M. A.: Inactivation of hepatic P450isozyme by 3,5-Dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine. Chem. Res. Toxicol. 2(6), 401-410 (1989) 6. Correia, M. A., Sugiyama, K. and Yao, K.: Degradation of rat hepatic Cyt.P450p. Drug Metabolism Reviews, 30(2-4), 615-628 (1989) 7. Decker, C. J. Cashman, J. R., Sugiyama,K. Maltby, D., and Correia, M. A.: Formation of glutathionylspironolactone disulfide by rat liver Cyt.P450 or hog liver flavin-containing monooxygenase.,Ch em. Res. Toxicol. 4(6). 669-677 (1991) 8. Smith, S. J., Korzekwa, K. R., Aoyama, T., Trager, F. J., Darbyshire, F. J. Sugiyama.,K., Gillette, J. R.: 12 Hydroxylation: a hitherto unidentified testosterone metabolite produced by Cyt.P4502A. Drug Metabolism Disposition, 20, 566 (1992) 9. Gillette, J. R., Darbyshire, J. F., and Sugiyama, K.: Theory for the observed isotope effects on the formation of multiple products by different mechanisms of cytochrome P450., Biochemistry, 33, 2927-2937 (1994) 10. Darbyshire, J. F., Gillette, R. J, Nagata, K, and Sugiyama, K.: Deuterium isotope effects on A-ring and D-ring metabolism of testosterone by CYP2C11: evidence for dissociation of activated enzyme-substrate complexes. Biochemistry, 33, 2938-2944 (1994) 11. Sugiyama, K., Nagata, K., Gillette, R. J, and Darbyshire, F. J.: Theoretical kinetics of Sequential metabolism in vitro: Study of the formation of 16 -hydroxyandrostenedione from testosterone by rat CYP2C11. Drug Met. Dispos. 22(4), 584-591 (1994). 12. Sugiyama, K., Correia, M. A., Thummel, K. E., Darbyshire, J. F., Osawa, Y., and Gillette, J. R.: pH-Dependent one-and two-electron type oxidations of 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine catalyzed by hemoproteins, horseradish peroxidase and cytochrome P450 3A4, Chem. Res. Toxicol. 7(5), 633-642 (1994) 13. Sugiyama, K., Hight, R. J., Woods, A., Cotter, R. J., Osawa, Y., and Gillette, J. R.: Characterization of a heme derivative during inactivation of horseradish peroxidase by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine. Chem. Res. Toxicol. 7(6), 843-849 (1994) 14. Sugiyama, K., Hight, R. J., Woods, A., Cotter, R. J., Gillette, J. R., and Osawa, Y.: Hydrogen peroxide-mediated alteration of the heme prosthetic group of metmyoglobin to an iron chlorin product; Evidence for a novel oxidative pathway, Proc. Natl. Acad. Sci. USA, 94, 796-801(1997) 15. Sato, S., Sugiyama, K. and Carper, D.: Aldose reductase as dihydrodiol dehydrognease: Naphthoquinone formation by rat lens aldose reuductase, Adv. Exp. Med. Biol. 414, 499-505 (1997) 16. Yong S. Lee, Chen, Z. and Kador, P. F. (Acknowledgements: Sugiyama, K.): Molecular modeling studies of binding modes of aldose reductase inhibitors at the active site of human aldose reductase. Bioorganic & Med. Chem., 6, 1811-1819 (1998) 17. Sugiyama, K. Wang, T-L, L, Simpson, J. T., Rodriguez, L.R. Kador, P. F. and Sato, S.: Aldose reductase catalyses the oxidation of naphthalenedihydrodiol for the formation of orth-napthoquinone. Drug Met. Dispos. 27(1), 60-67 (1999) 18. Sato, S., Sugiyama, K., Yong, S. Lee and Kador, P. F.: Prevention of naphthalene-1,2-dihydrodiol-induced lens protein modifications by structurally diverse aldose reductase inhibitors, Exp. Eye. Res. 68, 601-608 (1999) 19. Yong S. Lee, Sugiyama, K. and Kador, P. F.: Rotamers of tolrestat and their binding mode to aldose reductase, Enzymology and Molecular Biology of Carbonyl Metabolism, 7, 465-472 (1999) 20. Sugiyama, K., Yong, S. Lee, Chen, Z. and Kador, P. F.: Isolation of a Non-covalent aldose reductase-Nucleotide-inhibitor Complex. Biochemical Pharmacology, 59, 329-336 (2000) 21. Kador, P. F., Sun G., Rait, V. K., Rodriguez, L.R., Ma,Y. and Sugiyama, K.: Intrinsic inhibition of aldose reductase, 17(4), 373-381 (2001) 22. Sato, S., Sugiyama, K., Yong, S.: Oxidation of naphthalene-1,2-dihydrodiol to form 1,2-naphthoquinone: A key to event in formation of naphthalene cataract, Recent Rec. Devel. Drug Metabol. Disposition, 1[2002]:57-65 (2002) 23. Yong, S. Lee, Hodoscek, M., Kador, P. F. and Sugiyama, K.: Hydrogen bonding interactions between aldose reductase complexed with NADP(H) and inhibitor tolrestat studied by molecular dynamics simulations and binding assay, Chemico-Biological Interactions, 143-144, 307-316 (2003) 24. Yong, S. Lee, Marcu, M. G. and Neckers, L. (Acknowledgments: Sugiyama, K): Quantum chemical calculations and mutational analysis suggest heat shock protein 90 catalyzes trans-cisisomerization of geldanamycin, Chemistry& Biology, 11, 991-998 (2004)
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