Exposure to agrochemicals by humans, livestock and fish must be
determined in order to assess potential risks to farm workers and consumers.
 Experimental Study Descriptions
Workers involved in the preparation and application
of the agrochemical under normal field conditions are equipped with monitoring
devices (clothing, patches, air filters), which are extracted and analyzed to
determine the concentrations of active ingredients over time of exposure.
These studies are used to determine the surface
concentrations of active ingredients on leaves and turf that can be readily
removed and thus may constitute a hazard on re-entry. We have extensive
experience in designing and conducting such studies in both field and greenhouse
(ornamentals) settings.
PTRL West sub-contracts the in-life phase of these
studies, which generally utilize radiolabeled test substance. The analytical
phase is conducted in a manner similar to that of other animal metabolism
projects.
- Livestock Feeding Studies :
To determine the buildup and disappearance of
pesticide residues in livestock, cows and/or hens are orally dosed with various
concentrations of active ingredient with a predetermined regime. Milk and/or
eggs are analyzed frequently throughout a 28 day period and upon sacrifice the
edible tissues are also examined for concentrations of the test substance and
metabolites. We
conduct the in-life phase in collaboration with experienced laboratories and
farms under close monitoring by our Quality Assurance Unit.
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PTRL West 
